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Sapho amplified speculation and extrapolation, but it subjected its users to unpredictable outbursts of emotion or long periods of passivity. The Mentat addict's lethargy led him to neglect the constant updating of information upon which his accuracy depended. A measurable falling-off in reliability was a better indicator of Sapho addiction than its physical signs-ruby colored lips, a reddening of the skin-which could be concealed. Rehabilitation was possible, but relapses into the habit were frequent