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This war involved an extensive use of poison, but it was climaxed by the famous Lasgun Massacre, when Harkonnen mercenaries ambushed Duke Ira Pardee and his family at their hunting lodge on New Salem.
Various stories attribute this victory to the defection of the steward of their rural estate, a jealous functionary who was easily bribed. Undermining the loyalty of the retainers of another house was a specialty at which House Harkonnen seems to have excelled, according to the reputation of the house among others.